Real Science. Ancient Wisdom.

We blend traditional medicine with modern science and show you exactly how. No marketing BS. Just studies, sources, and radical honesty.

How we build our formulas
Our ingredient standards & Test results
What science-backed means

How We Build Our Formulas

We start with wisdom. We filter with evidence. We finish with clarity.

Traditional Use


We begin with centuries of proven use in Traditional Chinese Medicine, Tibetan medicine, and Ayurveda.

Modern Science

Each compound is cross-checked with modern clinical studies for real-world effectiveness.

Precision Dosing

We extract and dose only what works. No more, no less.

Nothing Extra

No blends. No fluff. Just one pure ingredient per product.

How We Build Our Formulas

We start with wisdom. We filter with evidence. We finish with clarity.

Traditional Use

Modern Science

Precision Dosing

Nothing Extra

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Our Ingredient Standards

We don’t compromise. Ever.

100% Fruiting Body Mushrooms

No mycelium. No grain. Just full-spectrum actives.

Sourced at Origin

Every ingredient is grown where it naturally thrives — in China, the birthplace of TCM.

No Fillers. No Additives. Ever.

We don’t bulk. We don’t fluff. We don’t hide.

Tested for Purity

Every batch tested for heavy metals, toxins, and identity

See our test results

What ‘Science-Backed’ Means at NÓNE

We don’t mean “sort of studied.” We mean proven, real-tested, peer-reviewed.

Cordyceps

Benefit Study & Year Type/Model Link
+11% VO₂ max (oxygen uptake) Hirsch et al., 2016 Human trial – Healthy adults View
Metabolic threshold +10.5%, Chen et al., 2010 DB‑RCT – Healthy older adults View
Improved exercise tolerance Yi et al., 2004 RDBPC – Older adults View
NK‑cell activity +38.8% Jung et al., 2019 DB‑RCT – Healthy adults View
Anti‑fatigue effect Song et al., 2015 In vivo – Mouse model View
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Lion’s mane

Benefit Study & Year Type/Model Link
Cognitive improvement Mori et al., 2009 RCT – Elderly with mild cognitive impairment View
MMSE score improvement Mori et al., 2009 RCT – Elderly View
NGF (Nerve Growth Factor) stimulation Kawagishi et al., 1994 In vitro (mouse cells) View
Increased hippocampal neurogenesis Nagano et al., 2010 RCT – Humans with mood disorders View
30% reduction in anxiety & depression Nagano et al., 2010 RCT – Women with stress symptoms View
Reduced amyloid plaque burden Mori et al., 2011 In vivo Alzheimer’s model View
Enhanced recognition memory Saitsu et al., 2019 RCT – Healthy adults View
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Pearl Powder

Benefit Study & Year Type/Model Link
Antioxidant status in humans (8 weeks, 3 g/d) Chiu et al., 2018 Randomized, placebo‑controlled – healthy adults View
Faster wound closure; ↑ collagen deposition Chen et al., 2019 In vitro + rat excision wound model View
UVA photoaging protection in skin Han et al., 2022 Mouse photoaging model + mechanistic View
Oral nacre extract: anti‑aging effects on skin & muscle Yamamoto et al., 2024 Animal (SAMP8 mice), oral administration View
Wound‑healing bioactivity of water‑soluble pearl components Liu et al., 2021 In vitro + in vivo (mouse) View
Clinical summaries incl. acne (73.3% cure with enzymatic pearl powder), pressure‑ulcer adjunct use Song et al., 2022 (review with clinical data) Human clinical reports (China), various designs View
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Shilajit

Benefit Study & Year Type/Model Link
↑ Total & free testosterone Pandit et al., 2016 Randomized, double‑blind, placebo‑controlled – healthy men View
↓ Strength loss after fatiguing exercise; ↓ baseline HYP (connective‑tissue marker) Keller et al., 2019 Randomized, double‑blind, placebo‑controlled – trained men View
↑ ECM (collagen/elastin) gene expression in skeletal muscle Das et al., 2016 Human longitudinal supplementation + biopsies View
↑ Post‑exercise muscle ATP and energy charge Bhattacharyya et al., 2009 Animal (mice), forced‑swim + supplementation View
Anti‑fatigue/behavioral improvement Surapaneni et al., 2012 Animal (mice), chronic fatigue model View
↑ Sperm count/motility; ↑ testosterone in oligospermia Biswas et al., 2010 Clinical trial – oligospermic men View
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Berberine

Benefit Study & Year Type/Model Link
↓ HbA1c & FPG; similar effect to metformin Yin et al., 2008 Randomized controlled trial – type 2 diabetes View
NAFLD: ↓ liver fat, improved insulin sensitivity Yan et al., 2015 Randomized, open-label, parallel trial – NAFLD patients View
NASH/diabetes: ↓ liver enzymes, weight reduction Harrison et al., 2021 Phase-2 randomized, placebo-controlled trial (berberine-UDCA salt) View
PCOS: improved metabolic features vs. metformin Wei et al., 2012 Randomized clinical trial – PCOS View
↓ Weight, BMI, waist circumference Asbaghi et al., 2020 Meta‑analysis of RCTs View
NAFLD: improved lipids, liver enzymes, insulin sensitivity Nie et al., 2024 Meta‑analysis of RCTs View
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Dragons Blood

Benefit Study & Year Type/Model Link
Faster wound healing with topical cream Namjoyan et al., 2015 Randomized, double‑blind, placebo‑controlled – human View
Accelerated cutaneous wound closure (dracorhodin perchlorate) Jiang et al., 2017 Rat wound model View
Keratinocyte migration & angiogenesis via β‑catenin Lu et al., 2021 In‑vitro (HaCaT) – mechanistic View
Review: hemostatic & wound‑healing properties Al‑Awthan et al., 2021 Review View
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