Science-backed. Traditionally proven.

We combine traditional healing arts with modern science and show you exactly how. No marketing bullshit. Just studies, sources, and radical honesty.

How we develop our formulas
Our ingredient standards & test results
What 'science-backed' really means

How we develop our formulas

We start with knowledge. We filter with evidence. We end with clarity.

Traditional Application

We begin with centuries of proven use in Traditional Chinese Medicine, Tibetan Medicine, and Ayurveda.

Modern Science

Every compound is cross-referenced with modern clinical studies for real, measurable efficacy.

Precise Dosing

We extract and dose only what works. No more, no less.

Nothing Superfluous

No blends. No unnecessary fillers. Just one pure ingredient per product.

How we develop our formulas

We start with knowledge. We filter with evidence. We end with clarity.

Traditional Application

Modern Science

Precise Dosing

Nothing Superfluous

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Our Ingredient Standards & Test Results

We never compromise. Ever.

100% Fruiting Body Mushrooms

No mycelium. No grain. Just full potency.

Sourced Directly at the Origin

Every ingredient is grown where it naturally thrives in China, the birthplace of TCM.

No Fillers. No Additives.

No fillers. No additives. No tricks.

Tested for Purity

Every batch is tested for heavy metals, contaminants, and authenticity.

See our Test Results

What 'Science-Backed' Means at NÓNE

For us, science-backed doesn't just mean tested somehow. It means: proven, verified, and peer-reviewed by experts.

Cordyceps

Benefit Study & Year Type/Model Link
+11% VO2 max Hirsch et al., 2016 Human study: Healthy adults View
Metabolic Threshold +10.5% Chen et al., 2010 DB-RCT: Healthy older adults View
Improved exercise tolerance Yi et al., 2004 RDBPC: Older adults View
NK-cell activity +38.8% Jung et al., 2019 DB-RCT: Healthy adults View
Anti-fatigue effect Song et al., 2015 In vivo mouse model View
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Lion’s mane

Benefit Study & Year Type/Model Link
Cognitive improvement Mori et al., 2009 RCT: Older adults with mild cognitive impairment View
MMSE-Score improvement Mori et al., 2009 RCT: Seniors View
NGF (Nerve Growth Factor) stimulation Kawagishi et al., 1994 In vitro (Mouse cells) View
Increased hippocampal neurogenesis Nagano et al., 2010 RCT: People with mood symptoms View
30% reduction in anxiety & depression Nagano et al., 2010 RCT: Women with stress symptoms View
Reduced amyloid plaque load Mori et al., 2011 RCT: Women with stress symptoms View
Reduced amyloid plaque load Saitsu et al., 2019 In vivo Alzheimer's model View
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Pearl Powder

Benefit Study & Year Type/Model Link
Antioxidativer Status bei Menschen (8 Wochen, 3 g/Tag) Chiu et al., 2018 Randomisiert, Placebo-kontrolliert gesunde Erwachsene View
Schnellere Wundheilung; Kollageneinlagerung Chen et al., 2019 In vitro + Rattenmodell Hautwunden View
UVA-Schutz gegen Hautalterung Han et al., 2022 Mausmodell Photoaging + Mechanistik View
Oraler Perlmutt-Extrakt: Anti-Aging-Effekte auf Haut & Muskeln Yamamoto et al., 2024 Tiermodell (SAMP8 Mäuse), orale Gabe View
Wundheilungsaktivität wasserlöslicher Perl-Komponenten Liu et al., 2021 In vitro + in vivo (Maus) View
Klinische übersicht inkl. Akne (73,3% Heilung mit enzymatischem Perlenpulver), Druckgeschwäre Song et al., 2022 (Review mit klinischen Daten) Menschliche klinische Berichte (China), verschiedene Designs View
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Shilajit

Benefit Study & Year Type/Model Link
Gesamt- & freies Testosteron Pandit et al., 2016 Randomisierte, doppelblinde, placebokontrollierte Studie gesunde Männer View
Kraftverlust nach ermüdendem Training; ↓ Basis-HYP (Bindegewebsmarker) Keller et al., 2019 Randomisierte, doppelblinde, placebokontrollierte Studie trainierte Männer View
ECM (Kollagen/Elastin) Genexpression in Skelettmuskeln Das et al., 2016 Humanstudie mit Supplementierung + Biopsien View
Post-Workout Muskel-ATP und Energieladung Bhattacharyya et al., 2009 Tiermodell (Mäuse), Forced-Swim + Supplementierung View
Anti-Fatigue / Verhaltensverbesserung Surapaneni et al., 2012 Tiermodell (Mäuse), chronisches Fatigue-Modell View
Spermienzahl/-beweglichkeit; Testosteron bei Oligospermie Biswas et al., 2010 Klinische Studie Männer mit Oligospermie View
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Berberine

Benefit Study & Year Type/Model Link
HbA1c & Nüchternblutzucker; ähnlicher Effekt wie Metformin Yin et al., 2008 Randomisierte kontrollierte Studie Typ-2-Diabetes View
NAFLD: Leberfett, verbesserte Insulinsensitivität Yan et al., 2015 Randomisierte, offene Parallelstudie NAFLD-Patienten View
NASH/Diabetes: Leberenzyme, Gewichtsreduktion Harrison et al., 2021 Phase-2 RCT Berberin-UDCA-Salz
PCOS: bessere metabolische Marker vs. Metformin Wei et al., 2012 Randomisierte klinische Studie – PCOS View
Gewicht, BMI, Taillenumfang Asbaghi et al., 2020 Meta-Analyse von RCTs View
NAFLD: verbesserte Blutfette, Leberenzyme, Insulinsensitivität Nie et al., 2024 Meta-Analyse von RCTs View
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Dragons Blood

Benefit Study & Year Type/Model Link
Schnellere Wundheilung mit topischer Creme Namjoyan et al., 2015 Randomisierte, doppelblinde, placebokontrollierte Studie Menschen View
Beschleunigte Hautwundheilung (Dracorhodin-Perchlorat) Jiang et al., 2017 Ratten-Wundmodell View
Keratinozytenmigration & Angiogenese über β-Catenin Lu et al., 2021 In-vitro (HaCaT) Mechanismus View
Review: hämostatische & wundheilungsfördernde Eigenschaften Al-Awthan et al., 2021 Überprüfen View
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